Treatments

ED Treatments & Products

Explore established medications, compounded formulations, devices, supplements, imported products, and products with uncertain regulatory status.

Evidence gradeSort

15 results

Gray-Market Product

“Rhino”-Branded Enhancement Pills

Claimed herbal blends (undeclared drugs found)

F

A loose product family with documented hidden drug ingredients; doses are unknown.

UNAPPROVEDGRAY MARKET
Type
Convenience-store enhancement pill
Regulatory
Unverified
Verification
Hidden Drugs Documented
Editorial
Investigation
Onset
Not established
Duration
Not established
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Gray-Market Product

“Royal Honey” Sexual-Enhancement Packets

Honey + claimed herbs (undeclared drugs found)

F

Marketed as natural, but this product category has documented hidden ED drug ingredients.

UNAPPROVEDGRAY MARKET
Type
Food-style product marketed for sexual performance
Regulatory
Unverified
Verification
Hidden Drugs Documented
Editorial
Investigation
Onset
Not established
Duration
Not established
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Other ED Treatment

Alprostadil Urethral Suppository

Alprostadil

B

Approved non-tablet option for people who cannot use PDE5 inhibitors.

FDA APPROVEDPRESCRIPTION
Type
Prescription intraurethral pellet
Regulatory
FDA Approved
Verification
Well Established
Editorial
Brief
Onset
5–10 min
Duration
30–60 min
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Prescription Medication

Avanafil

Avanafil

A

FDA-approved PDE5 inhibitor with a fast onset but less long-term real-world data.

FDA APPROVEDPRESCRIPTION
Type
Prescription PDE5 Inhibitor
Regulatory
FDA Approved
Verification
Well Established
Editorial
Reviewed
Onset
15–30 min
Duration
Up to 6 h
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Combination Product

Compounded Sildenafil + Tadalafil Troche

Sildenafil + tadalafil

C

Two approved ingredients combined in a formulation that has not been studied as a combination.

COMPOUNDEDPRESCRIPTION
Type
Compounded combination (sublingual troche)
Regulatory
Compounded Medication
Verification
Partially Verifiable
Editorial
Reviewed
Onset
Not established
Duration
Not established
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Supplement

Horny Goat Weed

Epimedium extract (icariin)

D

Lab-based rationale, but no solid human evidence for ED; product content varies.

SUPPLEMENT
Type
Herbal dietary supplement
Regulatory
Dietary Supplement
Verification
Label Claims Only
Editorial
Reviewed
Onset
Not established
Duration
Not established
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Imported Product

Imported Generic Sildenafil

Sildenafil citrate (claimed)

?

Established active ingredient, but the contents and dose of a given package cannot be independently verified.

IMPORTEDUNAPPROVED
Type
Foreign-manufactured generic
Regulatory
Foreign-Market Medication
Verification
Could Not Be Independently Verified
Editorial
Investigation
Onset
Unknown for a given product
Duration
Unknown for a given product
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Supplement

L-Arginine / L-Citrulline

L-arginine, L-citrulline

C

Amino-acid supplements with, at best, a small benefit in mild ED in limited studies.

SUPPLEMENT
Type
Amino-acid dietary supplement
Regulatory
Dietary Supplement
Verification
Label Claims Only
Editorial
Reviewed
Onset
Not established
Duration
Not established
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Prescription Medication

Sildenafil

Sildenafil citrate

A

Well-established prescription PDE5 inhibitor with predictable on-demand use.

FDA APPROVEDPRESCRIPTION
Type
Prescription PDE5 Inhibitor
Regulatory
FDA Approved
Verification
Well Established
Editorial
Full Profile
Onset
30–60 min
Duration
4–6 h
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Prescription Medication

Tadalafil

Tadalafil

A

Long-duration PDE5 inhibitor with both daily and on-demand dosing options.

FDA APPROVEDPRESCRIPTION
Type
Prescription PDE5 Inhibitor
Regulatory
FDA Approved
Verification
Well Established
Editorial
Full Profile
Onset
30–120 min
Duration
Up to 36 h
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Supplement

Tongkat Ali

Eurycoma longifolia root extract

C

Small, mixed studies on libido and testosterone; it does not work like ED medications.

SUPPLEMENT
Type
Herbal dietary supplement
Regulatory
Dietary Supplement
Verification
Label Claims Only
Editorial
Brief
Onset
Not established
Duration
Not established
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Compounded Product

Trimix Injection

Alprostadil + papaverine + phentolamine

B

Specialist compounded injection that can help when tablets fail, with a real priapism risk.

COMPOUNDEDPRESCRIPTION
Type
Compounded intracavernosal injection
Regulatory
Compounded Medication
Verification
Partially Verifiable
Editorial
Reviewed
Onset
5–20 min
Duration
Variable
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Device

Vacuum Erection Device

None (mechanical)

B

Drug-free mechanical option that avoids medication interactions.

FDA CLEARED
Type
Medical device
Regulatory
FDA Cleared Device
Verification
Well Established
Editorial
Brief
Onset
2–5 min
Duration
Up to 30 min (with ring)
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Prescription Medication

Vardenafil

Vardenafil hydrochloride

A

Established PDE5 inhibitor similar to sildenafil, with a distinctive QT-interval warning.

FDA APPROVEDPRESCRIPTION
Type
Prescription PDE5 Inhibitor
Regulatory
FDA Approved
Verification
Well Established
Editorial
Reviewed
Onset
25–60 min
Duration
4–5 h
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Supplement

Yohimbe

Yohimbe bark extract (yohimbine)

D

Stimulant-like extract with cardiovascular side effects and frequently inaccurate labels.

SUPPLEMENT
Type
Herbal dietary supplement
Regulatory
Dietary Supplement
Verification
Label Claims Often Inaccurate
Editorial
Reviewed
Onset
Not established
Duration
Not established
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