Pharmacology · 3 min read
What Does Half-Life Mean?
The time it takes for half a dose to leave your body.
- Written by
- SynMale Editorial
- Originally Published
- October 2026
- Last Updated
- October 2026
- Medical Review
- Not yet independently reviewed
A drug's half-life is the time for its blood concentration to fall by half. Sildenafil's is about 3–5 hours; tadalafil's about 17.5 hours. Longer half-life means longer effects—and longer side effects.